CORDIS Project
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This project explores the role of protein-tyrosine phosphatases in the formation of new blood vessels, a key process in conditions like cancer. It aims to identify how these proteins influence angiogenesis through targeted genetic manipulation in laboratory settings.
Angiogenesis is the formation of new blood vessels from pre-existing ones and is involved in different physiological and pathological processes such as cancer and ischemia.
Tyrosine phosphorylation is a reversible process, mediated by protein-tyrosine kinases (PTKs) and protein-tyrosine phosphatases (PTPs).
Although the role of PTKs in angiogenesis is well established, little is known about the function of specific PTPs in this process.
In collaboration with Dr. H.
Augustin, (Heidelberg, Germany…
Novartis Forschungsstiftung
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