CORDIS Project
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This project seeks to understand the mechanisms behind skeletal stem cell recruitment during bone healing, aiming to improve therapies for bone repair. It employs various mouse models to track stem cell behavior and assess factors influencing bone regeneration.
It is estimated that 2% of the population sustain fractures annually, which in Europe corresponds to approximately 15 millions fractures and in France 1 million fractures.
Although bone exhibits strong regenerative properties, delayed unions and non-unions still occur at a frequency of 5 to 10% in all skeletal injuries leading to patient disability and high societal cost.
Bone repair is dependent on the proliferation and differentiation of skeletal stem/progenitor cells.
The exact origins and fu…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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