CORDIS Project
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This research focuses on the role of TAM receptors in the immune system, particularly their involvement in the differentiation of macrophages in the spleen. By utilizing advanced genetic and imaging techniques, the project aims to uncover mechanisms that contribute to autoimmune disorders.
Chronic inflammation and dysregulation of the immune response underlie multiple human pathologies, including rheumatoid arthritis and systemic lupus erythematosus.
Autoimmune disorders comprise more that 50 distinct diseases and affect about 5% of the population in Europe.
Thus, chronic inflammation and autoimmunity are one of the thematic priorities within FP7 Cooperation Health (‘Other Chronic Diseases’).The TAM family of receptor tyrosine kinases - Tyro3, Axl and Mer – together with their act…
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