CORDIS Project
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This project investigates the role of specific receptors in retinal health, focusing on the mechanisms of retinal degeneration. It aims to understand how certain ligands influence the phagocytosis of photoreceptor cells, which could lead to new biomarkers for retinal diseases.
Macular and retinal degeneration are common blinding conditions which affect approximately 30% of individuals aged 75 years, and pose considerable socioeconomic burden.
Lack of the daily phagocytosis of photoreceptor outer segments (POS) by Retinal Pigment Epithelium (RPE) cells is the basis of such retinal degeneration (RD).
This proposal aims to characterize the role of TAM receptor Tyrosine Kinase signaling in maintaining healthy retinal homeostasis. TAM receptors (Tyro3, Axl, Mer) are homeos…
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Israel, Jerusalem
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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