CORDIS Project
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This project investigates how the mucin-like domain of the Ebola virus glycoprotein influences virus attachment and movement on cell surfaces. By creating pseudotyped viruses and employing advanced imaging techniques, the research aims to enhance understanding of viral behavior, which is crucial for developing effectiv…
Ebola virus, one of the deadliest human pathogens, is a known candidate for severe outbreaks and has caused several thousand deaths in the more recent outbreaks alone.
To fight against it, a detailed knowledge about its viral life cycle is fundamental to the development of efficient vaccines and drugs.
In this project I suggest to investigate the role of the mucin-like domain (MLD) of the viral glycoprotein (GP) in modulating virus attachment, detachment and diffusion on glycosaminoglycans (GAGs…
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