CORDIS Project
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This project investigates the functions of circular RNAs in the brain, focusing on their roles in gene expression and neuronal behavior. It aims to uncover how these regulatory molecules influence brain function through various mechanisms.
Tight regulation of RNA metabolism is essential for normal brain function.
This includes co and post-transcriptional regulation, which are extremely prevalent in neurons.
Recently, circular RNAs (circRNAs), a highly abundant new type of regulatory non-coding RNA have been found across the animal kingdom.
Two of these RNAs have been shown to act as miRNA sponges but no function is known for the thousands of other circRNAs, indicating the existence of a widespread layer of previously unknown gene…
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