CORDIS Project
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The PamGenes IOpener is an innovative diagnostic platform that predicts patient responses to immune checkpoint inhibitors before treatment begins. By analyzing kinase activity in immune cells from a blood sample, it aims to enhance precision medicine in cancer care and improve treatment outcomes for patients with early…
Cancer is the second leading cause of death worldwide, accounting for 10M deaths in 2020.
Although 7 Immune Checkpoint Inhibitors (ICI) are approved for different cancer indications and have represented a true breakthrough, only 10-50% of advanced cancer patients respond to the treatment.
This unpredictability of results, together with 15-60% severe toxicity rates and high prices are restricting the impact potential of ICIs.
Predicting ICI response is critical for fully realizing their potential…
PAMGENE INTERNATIONAL BV
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