CORDIS Project
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This project investigates the role of YAP/TAZ proteins in the size and metastatic potential of circulating tumor cell clusters in breast cancer. By analyzing these cells, the research aims to uncover mechanisms that could lead to new cancer therapies and better patient treatment strategies.
Metastasis is the leading cause of all cancer-related deaths.
Circulating Tumour Cells (CTCs) are cancer cells that shed off the primary tumour, enter into blood vessels and through the blood circulation are transferred to distant organs, whereby they establish new metastatic lesions. CTCs are detected as single cells and/or clusters of cells with clusters being more metastasis-prone than single CTCs. CTC clusters have different sizes varying from 2- to 50-cells.
However, it still remains unknow…
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
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