CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates how low-density lipoprotein accumulation in arteries relates to endothelial permeability and blood flow dynamics. It focuses on the role of sphingosine-1-phosphate in maintaining endothelial integrity under varying shear stress conditions, utilizing advanced imaging and modeling techniques.
Increased endothelial permeability allows accumulation of low-density lipoprotein (LDL) in the artery wall and may lead to atherosclerosis.
The spatial heterogeneity of atherosclerosis has been thought to implicate flow mediated effects in the development of the disease.
Indeed both in vitro and in vivo studies have shown a correlation between low or oscillating wall shear stress (WSS) and increases in atherogenic factors including increased endothelial permeability.
However, the mouse, which ha…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
