CORDIS Project
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This project explores the role of Type III secretion systems in Salmonella infections using zebrafish as a model organism. By tracking bacterial interactions in real-time, it aims to enhance understanding of how Salmonella manipulates host cells during infection.
Type III secretion systems (T3SS) are sophisticated “molecular needles” that many pathogenic Gram-negative bacteria use to establish infection.
Salmonella enterica encodes two T3SS that are able to translocate a number of proteins, called effectors, from bacteria to the cytosol of the infected eukaryotic cell.
These proteins manipulate host signal transduction pathways and cellular processes to the pathogen’s advantage.
During the last two decades, many studies have importantly contributed to th…
UNIVERSIDAD DE SEVILLA
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