CORDIS Project
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This study aims to uncover how the pathogen Salmonella Abortusovis evades the immune system in sheep, leading to abortions. It will explore the molecular mechanisms of infection and compare them to other Salmonella strains to enhance understanding of bacterial pathogenesis.
Abortion in sheep due to Salmonella enterica subspecies enterica serovar Abortusovis is an important animal health problem in areas of the Mediterranean, where the sheep industry has a significant economy impact.
The pathogen is host restricted to ovines where it invades the intestinal epithelium and causes a systemic infection that often goes undetected, until it manifest as an abortion.
In animals that are not pregnant, there are no overt signs of disease, suggesting that the organism can evad…
UNIVERSITA DEGLI STUDI DI SASSARI
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