CORDIS Project
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This project investigates the mechanisms of motility and virulence in Salmonella bacteria. It aims to understand how bacterial movement and secretion systems contribute to infection, with potential applications for developing new antimicrobial agents.
Salmonella are motile, gram-negative, pathogens that infect eukaryotic cells.
Outbreaks of salmonellosis are a great economic and health problem worldwide.
Many bacteria, like Salmonella, swim through liquid environments by rotating a helical organelle, the flagellum.
This sophisticated nanomachine is functionally and structurally related to virulence-associated type-III secretion systems (T3SS) of pathogenic bacteria.
The ability to move is of crucial importance for Salmonella virulence and inf…
HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH
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