CORDIS Project
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This project aims to develop a universal influenza vaccine using self-amplifying mRNA technology. By targeting key proteins from various flu strains, the vaccine seeks to provide broad protection against seasonal and pandemic variants, addressing the limitations of current seasonal vaccines.
Influenza (Flu) virus infections lead to thousands of deaths annually worldwide and billions of dollars of economic burden.
Vaccination is the primary strategy for Flu prevention; however, effective protection requires a perfect match with the seasonal circulating strains.
Seasonal vaccines target the hemagglutinin (HA) and neuraminidase (NA) proteins of the two predominant A and one B circulating strains, and induce high neutralizing antibody titers.
Emerging Flu viruses escape host immunity by…
GLAXOSMITHKLINE VACCINES SRL
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