CORDIS Project
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This project focuses on improving treatments for HER2-positive breast cancer by targeting the endosomal trafficking of the HER2 protein. By enhancing the effectiveness of existing therapies and reducing resistance, the project aims to provide a new treatment option for patients who do not respond to current medications…
HER2+ breast cancers are an aggressive type of breast cancer and have a poor prognosis.
There are many therapies currently on the market to target this type of cancer, however they fail to deliver effective clinical results due to therapy resistance.
In our ERC-CoG project, we found that proper endosomal trafficking is required for functional HER2 oncogenic signalling at the plasma membrane.
Targeting HER2 endosomal traffic can result in effective treatment of HER2+ cancers, without the risk of…
TURUN YLIOPISTO
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