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The SCAN project focuses on developing new methods for breaking carbon-nitrogen bonds in amines, leveraging oxidative deamination pathways. By creating innovative redox-active amines and utilizing advanced catalysis techniques, it aims to enhance the functionalization of complex molecules, particularly in pharmaceutica…
Amines are ubiquitous across natural products, pharmaceuticals, polymers and biomolecules.
The number of commercially available amines, from simple to complex, makes them one of the most accessible native functional groups.
Therefore, they represent an attractive feedstock for the preparation of functionalized molecules through C-N bond activation.
Nature long ago developed protocols to promote oxidative deamination reactions.
Inspired by this approach, SCAN (Selective Pathways for CArbon-Nitrog…
UNIVERSIDAD AUTONOMA DE MADRID
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