CORDIS Project
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This research focuses on understanding gene regulation at the single-cell level to explain cellular states in complex tissues. It aims to develop new algorithms for analyzing transcriptional and epigenomic data from individual cells.
Robust and flexible tissue- and cell-type specific gene regulation is a definitive prerequisite for complex function in any multi-cellular organism.
Modern genomics and epigenomics provide us with catalogues of gene regulatory elements and maps illustrating their activity in different tissues.
Nevertheless, we are far from being able to explain emergence and maintenance of cellular states from such data, partly because we so far lacked characterization of individual molecular states and genome c…
WEIZMANN INSTITUTE OF SCIENCE
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