CORDIS Project
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This project aims to investigate the molecular mechanisms behind GATA2 deficiency, a disorder linked to severe blood-related diseases. By utilizing advanced genetic analysis and stem cell technology, it seeks to uncover the genetic variations and regulatory networks involved in disease progression, ultimately aiding in…
Precision medicine has improved overall survival of cancer patients; unfortunately, not all diseases can benefit from this practice due to a scarce understanding of their molecular mechanisms.
This is the case of GATA2 deficiency, a complex multi-system disorder characterized by bone marrow failure, immunodeficiency and high risk to develop myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML).
Chemotherapy and allogenic hematopoietic stem cell (HSC) transplantation are the only availa…
FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE
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