CORDIS Project
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This project investigates the role of cyclic dimeric adenosine monophosphate (c-di-AMP) in bacterial signaling and differentiation using Streptomyces as a model. It aims to uncover how c-di-AMP influences stress adaptation and antibiotic production, potentially revealing new targets for drug development.
Sophisticated signalling systems enable bacteria to occupy almost every single niche on our planet.
In such systems, second messengers are crucial information carriers that elicit cellular adaptation to diverse signals.
Current dynamics in signalling research have led to the discovery of an exquisite collection of nucleotides that bacteria use as second messengers, including cyclic dimeric adenosine monophosphate (c-di-AMP). A unique feature of c-di-AMP is its essentiality, making it an attracti…
GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER
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