CORDIS Project
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This project aims to develop a toolkit of genetically modified cell lines and specialized culture media to accurately represent various solid tumor subtypes. By improving in vitro models, the project seeks to enhance drug discovery processes and reduce the high failure rates associated with anticancer treatments.
Cancer is a very heterogeneous disease and its subtypes display great variability in their response to treatment.
The high failure rate of anticancer drug discovery consumes billions of dollars annually, contributing to the high cost of those few drugs that are eventually approved.
One of the problems lies in inaccurate and oversimplified cell line models for studying human tumors.
Yet, a method to incorporate tumour subtype contribution in response to drugs is lacking.
To improve experimental o…
MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (MDC)
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