CORDIS Project
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This project focuses on the therapeutic potential of neural progenitor cells in protecting the central nervous system from degeneration. It aims to understand the mechanisms of communication between these cells and their neighbors, particularly through the transfer of small non-coding RNAs.
Compelling evidence exists that somatic stem cell-based therapies protect the central nervous system from chronic inflammation-driven degeneration, such as that occurring in experimental autoimmune encephalomyelitis and stroke.
It was first assumed that stem cells directly replace lost/damaged cells, but it has now become clear that they are able to protect the damaged nervous system through mechanisms other than cell replacement.
In immune-mediated experimental demyelination and stroke we have…
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