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SENFIB aims to develop new drugs targeting fibrotic diseases by selectively eliminating senescent cells, which contribute to conditions like idiopathic pulmonary fibrosis and chronic kidney disease. The project focuses on discovering senolytic molecules that can improve organ function and viability in aging populations…
SENFIB aims to deliver new drugs for the treatment of fibrotic diseases.
Nearly one quarter of the global population will be over the age of 65 by 2050.
Populations over 65 suffer from multiple degenerative diseases including tissue fibrosis, estimated to account for upwards of 45% of all-cause mortality.
Animal models have demonstrated that senescent cells are causative in many fibrotic diseases including lung (i.e. idiopathic pulmonary fibrosis, IPF), and chronic kidney disease (CKD).
Senescen…
FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)
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