CORDIS Project
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This research focuses on understanding the evolution of cartilage by studying the genetic regulation of cartilage cells in the cephalopod mollusk, Sepia officinalis. The project aims to identify genes involved in cartilage development and their implications for vertebrate evolution.
The presence of cellular cartilage-like tissues outside the chordate lineage is either indicative of a common origin of cartilage as a metazoan tissue type (homology), or alternatively highlights developmental and/or structural constraints in constructing an internal cellular support tissue or endoskeleton (convergence).
If a genetic program for specifying chondrocytes (cartilage cells) arose only once during metazoan evolution, there should exist a molecular fingerprint that is common amongst a…
BIOGEM scarl
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