CORDIS Project
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This project investigates the impact of biological sex on cell death during ischaemia/reperfusion injury in acute myocardial infarction. By studying both mouse and human hearts using advanced techniques, it aims to uncover sex-based differences that could lead to new therapeutic targets in cardiovascular medicine.
Acute myocardial infarction (MI) accounts for millions of morbidity and mortality cases worldwide.
While the underlying pathophysiology of cardiomyocyte dysfunction and death during MI-related ischaemia/reperfusion injury (IRI), which occurs due to the restoration of coronary blood flow after MI, is well established, the relevance of sex-based differences in this context is poorly understood.
In this action, we aim at understanding the effect of biological sex in the induction of a novel form of…
HASKOLI ISLANDS
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