CORDIS Project
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This project investigates how cells adapt to shape changes in dense tissue environments, focusing on immune and cancer cells. It aims to uncover the molecular mechanisms behind these adaptations and their implications for immunity and cancer progression.
Cells are often depicted as irregular spherical objects - the shape they adopt in suspension.
However, the packed environment of tissues alters this simple shape, causing large cell deformations.
This occurs during normal tissue growth and is even more pronounced upon tissue overgrowth, as in the case of solid tumors.
Cell shape changes frequently occur in migratory cells, such as immune cells that patrol the organism within interstitial tissues, and cancer metastases that escape from the primar…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
France, Paris
Type: Research institute
Activity type: Research Organisations
SME: No
France, Paris
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
ISTITUTO EUROPEO DI ONCOLOGIA SRL
Italy, Milano
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: No
Italy, Milano
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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