CORDIS Project
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This project aims to innovate the synthesis of five-membered ring heteroaromatics, crucial for medicinal and agricultural chemistry. It seeks to develop a new catalytic method that allows for versatile substitution patterns, enhancing the functionality of these compounds.
Five-membered ring heteroaromatics such as pyrroles, furans, thiophenes and isoxazoles form a cornerstone of medicinal and agrochemical research.
Despite this importance, the predominant methods used by both academic and industrial researchers to access these frameworks still rely on chemistry developed up to a century ago, which suffers from several drawbacks.
Chief amongst these is the restriction on substituent pattern that is intrinsic to these classical routes, which prevents decoration of…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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