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The SHIFT project investigates how sex hormones influence antiviral immune responses, particularly in the context of individuals undergoing sex-reassignment therapy. By examining these mechanisms, the project aims to enhance understanding of sex differences in immunity, which could inform the development of targeted an…
COVID-19 severity and mortality are consistently higher in men than women.
Still, the mechanisms that underlie sex differences in human antiviral immunity remain poorly understood.
Therefore, investigating sex-specific regulation of immune responses is a critical step for developing novel and effective antiviral therapies.
The overarching goal of SHIFT is to dissect the precise contribution of sex hormones to human antiviral immune function by studying the immune system of individuals as they un…
KAROLINSKA INSTITUTET
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