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The SIGNAL project investigates the role of neuro-sentinel innate lymphoid cells in the lung, focusing on how they respond to neural signals. This research aims to enhance our understanding of neuroimmune interactions, particularly in relation to asthma and allergies, potentially leading to new treatment pathways.
The immune system is indispensable for our defense against infections, and plays an essential role in homeostasis, where compartmentalization and specialization are key aspects of every immune cell.
Microenvironmental cues (e.g. stromal cell-derived signals) are integrated by the cell networks forming the immune system to maintain immune tolerance or promote immunity against an antigen.
Recent findings suggest that neurons also contribute to curb the immune response; they produce neuropeptides t…
UNITED KINGDOM RESEARCH AND INNOVATION
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