CORDIS Project
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This project investigates G Protein Coupled Receptors (GPCRs) and their assembly into complexes that enhance cellular responses. Focusing on the mGlu2-5HT2A heteromer linked to schizophrenia, the research aims to understand how these complexes function and their potential as drug targets.
G Protein Coupled Receptors (GPCRs) are key mediators of how cells sense and react to their outside environment.
Traditionally, these receptors have been thought to function as individual units at the cell surface.
Over the past decade, new evidence has shown they can assemble in larger complexes to form new signaling entities and vastly expand a cells capacity to respond to its environment.
Thanks to their strong tissue-specificity, these complexes -termed heteromer- also form important targets…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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