CORDIS Project
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This project investigates how signaling dynamics influence cell proliferation and differentiation during development and tissue maintenance. By utilizing advanced microscopy and organoid culture, it aims to uncover the role of dynamic signaling in multicellular systems, focusing on somitogenesis in vertebrate embryos a…
Tight coordination between proliferation and differentiation is key to proper development and homeostasis of multicellular systems.
Cell-cell communication via signaling pathways has long been studied in this context.
Encoding information in the temporal change of a signal, i.e. signaling dynamics, can ensure information transmission to be specific and accurate.
Studies exemplifying the relevance of dynamic signaling raise the critical question:
What is the function of signaling dynamics in cont…
KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW
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