CORDIS Project
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This project aims to identify and characterize silencer elements in the human genome, which play a crucial role in gene regulation. By developing a novel identification system, it seeks to enhance understanding of gene expression and its implications for diseases.
Less than 1.5% of the human genome contains protein coding information of the estimated 25,000 genes.
The rest of the non-coding genome includes many regulatory elements that control the spatial and temporal transcription of genes.
With the help of the non-coding regulatory elements, the diverse cell types and tissues of a complex human body could be derived from the combinational expression of a limited number of genes from the same copy of the genome.
Most regulatory elements (REs) have been c…
Leiden University Medical Center
ACADEMISCH ZIEKENHUIS LEIDEN
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