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The SilentFACT project investigates the role of a chromatin regulator called FACT in cancer. By utilizing advanced genomic and proteomic techniques, the project aims to identify how FACT influences cancer cell growth and to develop small molecules that target this protein for potential therapeutic use.
Our knowledge of the mechanisms underlying cancer rapidly evolves.
Diagnosis and treatment are improving, but cancer remains an urgent health burden.
Whole-genome sequencing of cancers by the International Cancer Genome Consortium reveals that a key driving force in the etiology of cancer is the abnormal expression of chromatin regulators.
The SilentFACT project focuses on an essential regulator of chromatin structure, the histone chaperone FACT.
Recently identified small molecules disrupt norma…
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
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