CORDIS Project
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SilentFlame explores the immune response to specific bacterial components in chronic inflammatory diseases like Crohn's disease and myalgic encephalomyelitis. The project investigates how these components interact with the immune system and their role in sustaining inflammation.
The last century has seen a dramatic increase in the prevalence of chronic inflammatory and autoimmune illnesses, including diseases of poorly understood etiology such as Crohn’s disease (CD) and myalgic encephalomyelitis (ME).
Recent reports for CD and ME of elevated levels of antibodies against flagellins made by Lachnospiraceae (Lachno), which are usually associated with health, suggest a common breakdown of immune tolerance.
My laboratory recently discovered a new class of flagellin that we…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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