CORDIS Project
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This project investigates the cellular mechanisms of apoptosis in neurons under oxidative stress, aiming to understand how these processes contribute to ischemic stroke and neurodegenerative diseases. It employs advanced imaging techniques for real-time analysis.
Ischaemic stroke and neurodegenerative disorders are leading causes of death and disability and their incidence is rising rapidly due to increases in European life expectancy.
Excessive apoptosis is pathogenic when it concerns post-mitotic cells such as neurons; for instance in stroke or neurodegenerative diseases.
Oxidative stress is a major contributor to ischemic and neurodegenerative processes; however, the molecular mechanisms and biological switches that determine outcome, i.e. neuronal to…
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