CORDIS Project
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This research focuses on analyzing gene regulation at the single-cell level during early embryonic development. By utilizing advanced sequencing technologies, it aims to uncover the complexities of gene expression and regulatory mechanisms in pluripotent cells, which could inform future stem cell therapies.
We aim to study transcriptomes with single-cell resolution, a long-standing goal in biology, to answer fundamental questions about gene regulation.
The main objective concerns gene regulation during in vivo differentiation and in pluripotent cells by studying single-cells from murine preimplantation embryos, a model system with natural single-cell resolution, important biology and medical potential.
This would also allow us to explore general regulatory principles of gene expression programs of…
KAROLINSKA INSTITUTET
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