CORDIS Project
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This project focuses on understanding how proteins are transported through cell membranes, a process vital for cellular function. By creating innovative laboratory tools, the research aims to study the mechanics of protein translocases, which are crucial for both normal cell operations and the actions of certain pathog…
The threading of proteins through narrow channels within a cell is a crucial biological process, which is essential for cellular protein trafficking and protein degradation.
This translocation process is also used by pathogens such as anthrax and C.
Difficile, which inject their lethal toxins through the cell membrane in order to hijack vital cell machinery.
The motor proteins driving this translocation process are called protein translocases.
Despite the ubiquity of protein translocation in bi…
TECHNISCHE UNIVERSITEIT DELFT
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