CORDIS Project
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This project investigates the role of SIRT7 and PAX5 in B cell development and acute lymphoblastic leukemia. By understanding how these proteins interact, the research aims to uncover new strategies to enhance PAX5 levels, potentially improving treatment options for patients with this common pediatric cancer.
Acute lymphoblastic leukemia, the most common pediatric cancer, originates in many cases from the malignant transformation of a developing Blymphocyte in the bone marrow.
Understanding the mechanisms of B cell maturation and how their perturbation contributes to the onset of this pathology is essential for evolving improved strategies for those patients not responding to current therapies.
Importantly, this project aims to discover novel mechanisms of B lymphopoiesis by studying the interplay be…
INSTITUT JOSEP CARRERAS - CERCA
FUNDACIO INSTITUT DE RECERCA CONTRA LA LEUCEMIA JOSEP CARRERAS
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