CORDIS Project
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The SIRT7-LC project investigates the role of the SIRT7-nucleophosmin axis in lung cancer, focusing on how this interaction influences the activity of the c-Myc oncogene and cancer cell proliferation. By understanding these molecular mechanisms, the project aims to identify new therapeutic targets for lung cancer treat…
Lung cancer is the second cause of death due to malignancy and diagnosed patients rarely survive beyond two years.
Thus, unveiling the molecular mechanisms underlying lung tumorigenesis is imperative for development of novel therapeutic approaches.
The nucleolar protein nucleophosmin (NPM) plays critical roles in cancer progression and is often deregulated in human malignancies. NPM employs distinct mechanisms to control cancer cells growth including regulation of the proto-oncogene c-Myc, a tra…
INSTITUT JOSEP CARRERAS - CERCA
FUNDACIO INSTITUT DE RECERCA CONTRA LA LEUCEMIA JOSEP CARRERAS
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