CORDIS Project
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This project investigates how cells regulate their size through a novel microscopy technique. By tracking the dynamics of specific proteins in unicellular organisms, it aims to uncover the molecular mechanisms behind cell-size control and the influence of genetic factors like ploidy.
Cells have strict control over their size to ensure proper cell physiology.
They also have ways to correct for deviations, referred to as cell-size homeostasis, leading to a very narrow distribution in cell size at division.
Although some of the genes involved in this process have been identified, the underlying molecular mechanism has remained elusive.
One possibility is that the cell can “sense” its size through a protein whose concentrations are related to cell-size ‒ known as the sizer mode…
THE FRANCIS CRICK INSTITUTE LIMITED
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