CORDIS Project
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This project investigates how epidermal stem cells differentiate and position themselves within the skin. By utilizing advanced imaging techniques and computational modeling, it aims to understand the impact of cell shape and mechanical forces on stem cell behavior and tissue development.
As a self-renewing organ maintained by multiple distinct stem cell populations, the epidermis represents an outstanding, clinically relevant research paradigm to address mechanisms of stem cell regulation.
To achieve the dynamic turnover and maintenance of the critical skin barrier function, epidermal stem cells (SC) commit to differentiate and delaminate from the basal layer to form suprabasal layers.
What triggers SC differentiation, how the differentiating cells move upwards, and how differen…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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Finland, HELSINGIN YLIOPISTO
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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