CORDIS Project
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The project aims to create a novel ex vivo melanoma graft model, SkinModelOma, to study tumor growth and evaluate new therapies for skin cancer. This model will incorporate human skin tissue and multicellular spheroids to better mimic human conditions.
One of the biggest limitations in developing new treatments for cutaneous melanoma relies on overcoming the inefficient screening, often to animal models, which greatly differ from humans.
Also, the 3Rs principle limits the number of therapeutics that actually reach the in vivo evaluation of product/drug development or discovery.
Thus, there is a high demand for novel pre-clinical platforms, as alternative models to the use of animals, that can screening new treatments. I propose the establish…
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