CORDIS Project
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This project seeks to develop a new panel of transplantable mouse lung cancer cell lines with specific mutations for cancer research and drug discovery. It aims to create a reliable source of cell lines that reflect human cancer biology more accurately.
This project aims to protect, and commercialize a new panel of transplantable mouse lung cancer cell lines with defined mutation status (MLC) for cancer research and drug discovery.
In addition, we aim at disseminating and exploiting a novel method for generating an unlimited pool of such lines from various strains of mice.
Human lung cancer is characterized by a variety of mutations in oncogenes (i.e., KRAS) and tumor suppresors (i.e., TRP53), which largely determine whether lung tumors respond…
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