CORDIS Project
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This research investigates the role of ubiquitination in transforming TGF-beta growth factor signaling, which is vital for embryonic development and various diseases. The project aims to explore how modifying this signaling pathway can influence cell differentiation and cancer progression.
The research here outlined deals with the relevance of ubiquitination in TGF-beta growth factor signalling.
As outlined below (subchapters) TGF-beta signalling is fundamental for embryonic development and for a variety of human pathologies.
In particular, recent data showed that tuning TGF-beta signalling is essential for differentiation of pluripotent cells and for cancer and metastasis.
The proposal is therefore highly relevant not only scientifically but also for the socio-economic reasons. W…
UNIVERSITA DEGLI STUDI DI PADOVA
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