CORDIS Project
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This project investigates the role of small RNAs in defending against giant virus infections in unicellular eukaryotes. By studying the relationship between viral integrations and RNA responses, it aims to uncover potential immunity mechanisms against these viruses.
In this project, we aim to investigate the role of small RNAs (sRNAs) in defending against giant virus infections.
Giant viruses are eukaryotic viruses with exceptionally large genomes, some of which surpass the size of bacterial genomes.
Remarkably, giant virus integrations have been found across various eukaryotes, leading to the formation of giant endogenous viral elements (GEVEs).
Among the reported GEVEs, the host group (Dr. de Mendoza’s laboratory) has identified a unicellular relative of…
QUEEN MARY UNIVERSITY OF LONDON
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