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SMART-DNA aims to enhance the detection of single molecule reactions using artificial DNA nanostructures. By precisely positioning nanoparticles and target molecules, the project seeks to improve the understanding of chemical reaction mechanisms and develop new strategies for cancer therapies.
The monitoring of single molecule reactions promises unrivalled insight into chemical reaction mechanisms, but represents one of the most challenging tasks in chemistry.
Surface-enhanced Raman scattering (SERS) is a particularly attractive single molecule (SM) technique due to its high chemical specificity, which allows to directly detect relevant intermediates and molecular subpopulations.
However, SM-SERS is still at a premature state due to the highly challenging task to place single molecule…
UNIVERSITAET POTSDAM
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