CORDIS Project
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This project focuses on developing advanced anti-tumor agents using titanium(IV) complexes. It aims to create pH-sensitive transport units for targeted drug delivery, ensuring stability and controlled release of therapeutic compounds in specific human tissues.
I propose to develop sophisticated anti-tumor agents targeted particularly to the location of activity.
My team has recently introduced a new family of Ti(IV) complexes that demonstrates higher activity than known compounds with substantially higher stability and defined hydrolytic behavior, properties that were found to be essential. I propose to study various derivatives and identify the parameters affecting activity, including steric and electronic effects, enantiomeric purity, ligand labilit…
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