CORDIS Project
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This project aims to develop a new technology for studying single native enzymes using nanopores. By observing ionic flow disruptions caused by enzyme interactions, the method provides insights into enzyme behavior and conformational changes, enabling detailed studies of biological processes at the single-molecule leve…
Single molecules based techniques provide the ultimate toolkit to study complex biological systems.
In single-molecule approaches, molecules do not need to be synchronised as in ensemble studies, and rare and/or transient species along a reaction pathway as well as heterogeneity and disorder in a sample can be revealed.Observing and manipulating single molecules, however, is generally complicated, time consuming and withstand several technical limitations that hamper the study of single enzymes…
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Belgium, Leuven
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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