CORDIS Project
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This project investigates the role of the protein SMOC2 in joint health, particularly focusing on osteoarthritis. It combines laboratory studies with animal models and patient data to explore SMOC2 as a potential therapeutic target for improving osteoarthritis diagnosis and treatment.
This project will study the role of SMOC2 in the biology and pathology of synovial joints with specific attention towards osteoarthritis (OA), one of the most common chronic diseases. SMOC2 is a novel secreted protein that can interact with bone morphogenetic protein (BMP) and Wingless-like (Wnt) signaling key pathways in joint development, homeostasis, disease and repair.
We will use a translational research approach combining in vitro data with mechanistic insights obtained in a well character…
KATHOLIEKE UNIVERSITEIT LEUVEN
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