CORDIS Project
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This project aims to create a new method in structural biology to analyze complex protein assemblies using single molecule fluorescence resonance energy transfer (smFRET) and computational modeling. It focuses on the yeast ESCRT machinery, which is crucial in HIV infections.
We seek to develop a new structural biology method that is able to overcome barriers to solving very complex functional protein assemblies that are variable enough in their composition and conformation to defeat current methodologies. I intend to combine high-throughput single molecule FRET (smFRET) experiments with computational modeling to achieve this goal.
SmFRET will be used to derive individual building block structures as well as distances between these blocks on a molecule-to-molecule le…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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LOS ANGELES UCLA SANTA BARBARA UCSB DAVIS UCD RIVERSIDE UCR SAN DIEGO UCSD SANTA CRUZ UCSC IRVIN
United States, Berkeley
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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