CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the role of a specific microRNA, miR-145561, in regulating immune responses and maintaining immune balance. By studying knockout mice, the research aims to understand how this microRNA influences lymphocyte function and contributes to autoimmune disease mechanisms.
MicroRNAs constitute an essential, evolutionary conserved mechanism of posttranscriptional gene expression regulation and thereby affect almost all biological processes including immune functions.
In a comprehensive small RNA profiling study we identified a new, Snord104-derived microRNA, miR-145561, which is highly expressed in activated mature lymphocytes.
To investigate the role of this lymphocyte-predominant microRNA we generated miR-145561 knockout mice.
Aging miR-145561-deficient mice pres…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
