CORDIS Project
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This project investigates how past social experiences influence the brain's response to social threats in mice. By examining synaptic changes in a specific brain region, it aims to uncover mechanisms that could lead to new treatments for psychiatric disorders linked to social adversity.
The ability to learn and adapt in response to diverse social experiences is fundamental for animal survival.
While key defensive actions against social threats such as flight or fight are innate, previous social experience can guide the selection of the appropriate response to minimize future harm, such as the development of social avoidance following social defeat.
The ventromedial hypothalamus is a key brain structure in the innate defensive system, and activity in its ventrolateral part (VMHv…
EUROPEAN MOLECULAR BIOLOGY LABORATORY
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